Management of pain in chronic pancreatitis is a challenging clinical problem. Lack of proper understanding of the mechanisms responsible for pain, high morbidity and mortality rates historically associated with pancreatic surgery, and the long held view that pain will eventually subside when the pancreas "burns itself out" as a result of progressive fibrosis have all contributed to a non-surgical therapeutic approach for decades. Many recent studies have challenged this view, and at present there is a shift from the "wait and see" approach to a more pro-active type of therapeutic approach in the management of pancreatic pain.
Ceylon Medical Journal Vol. 53, No. 1, March 2008 pp.1-3