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Correspondence

Multiple autoimmune phenomena preceding a lymphoproliferative disorder

Author:

Suranjith L Seneviratne

St Mary's Hospital and Imperial College London, United Kingdom, GB
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Abstract

Karunatilake and Pidcock  recently described an interesting patient with autoimmune manifestations, cytopenias and lymphoproliferation. However, the authors did not comment on several important aspects. Did the patient have any lymphadenopathy, and was there a family history of a similar condition? Was the presence of double negative T cells in the peripheral blood looked for, was an aptotosis assay done, and if abnormal, were relevant Fas pathway gene defects looked for? The patient described may in fact have had the autoimmune lymphoproliferative syndrome (ALPS).  

doi:10.4038/cmj.v53i2.242

Ceylon Medical Journal Vol. 53, No. 2, June 2008 pp.72
DOI: https://doi.org/10.4038/cmj.v53i2.242
How to Cite: Seneviratne, S.L., 2008. Multiple autoimmune phenomena preceding a lymphoproliferative disorder. Ceylon Medical Journal, 53(2), p.72. DOI: http://doi.org/10.4038/cmj.v53i2.242
Published on 12 Dec 2008.

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