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Chronic hypernatraemia due to osmoreceptor dysfunction

Authors:

WMHS Chandrasekara ,

Section of Endocrinology, Departments of Medicine, Caerphilly Miners' Hospital, St. Martin's Road, Caerphilly, GB
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S Thondam,

Section of Endocrinology, Departments of Medicine, Caerphilly Miners' Hospital, St. Martin's Road, Caerphilly, GB
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MD Penney,

Chemical Pathology, Caerphilly Miners' Hospital, St. Martin's Road, Caerphilly, GB
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LDKE Premawardhana

Section of Endocrinology and 3Centre for Endocrine and Diabetes Sciences, University Hospital of Wales, Heath Park, Cardiff CF14 4 XN, UK, GB
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Abstract

Plasma osmolality is regulated by the interaction of the kidneys, arginine vasopressin (AVP), and thirst - the last two being stimulated by hypothalamic osmoreceptor signals. Osmoreceptor dysfunction may cause hypernatraemia, hyperviscosity and considerable morbidity, and may be associated with other endocrine dysfunction. We report two patients with chronic hypernatraemia and osmoreceptor dysfunction.  

doi: 10.4038/cmj.v53.i3.258

Ceylon Medical Journal Vol. 53, No. 3, September 2008 pp111-112

Keywords: hypernatraemia  
DOI: https://doi.org/10.4038/cmj.v53i3.258
How to Cite: Chandrasekara, W., Thondam, S., Penney, M. and Premawardhana, L., 2008. Chronic hypernatraemia due to osmoreceptor dysfunction. Ceylon Medical Journal, 53(3), pp.111–112. DOI: http://doi.org/10.4038/cmj.v53i3.258
Published on 17 Dec 2008.

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