Case Reports
A case of distal renal tubular acidosis, Southeast Asian ovalocytosis and possible fluorosis
Authors:
JP Vithanage ,
General Medical Unit (Ward 45), National Hospital of Sri Lanka, Colombo, LK
M Ekanayake
General Medical Unit (Ward 45), National Hospital of Sri Lanka, Colombo, LK
Abstract
A 39-year old man had periodic paralysis due to hypokalaemia. Investigations led to the diagnosis of distal renal tubular acidosis (dRTA) and Southeast Asian ovalocytosis (SAO). Both can originate in mutations of the anion-exchanger 1 gene (AE1), which codes for band 3, the bicarbonate/chloride exchanger in both the red cell membrane and the basolateral membrane of the collecting tubule alpha-intercalated cell. The finding of diffuse osteosclerosis led to the suspicion of coexisting fluorosis.
doi: 10.4038/cmj.v54i1.469
Ceylon Medical Journal Vol.54(1) 2009 p.19-20
How to Cite:
Vithanage, J. and Ekanayake, M., 2009. A case of distal renal tubular acidosis, Southeast Asian ovalocytosis and possible fluorosis. Ceylon Medical Journal, 54(1), pp.19–20. DOI: http://doi.org/10.4038/cmj.v54i1.469
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Published on
21 Apr 2009.
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