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A case of POEMS syndrome with mixed hyaline vascular and plasma

Authors:

K P Ruwan C Parakramawansha ,

Neurology Unit, Teaching Hospital, Kandy, Sri Lanka, LK
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I Wijeweera,

Neurology Unit, Teaching Hospital, Kandy, Sri Lanka, LK
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Neelakanthi Ratnatunga,

Department of Pathology, University of Peradeniya, LK
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W G V Sumanasekara

Neurology Unit, Teaching Hospital, Kandy, Sri Lanka, LK
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Abstract

We report a 43-year old man who developed progressive ascending sensorimotor polyneuropathy, a solitary bone plasmacytoma originating from a rib and an axillary lymph node with features of Castleman's disease, mixed hyaline vascular and plasma cell type. He was diagnosed of having non-Hodgkin's lymphoma seven years back and was treated. Examination revealed a smooth goitre, thickened skin, white nails, small testes and ankle oedema. Investigations revealed a monoclonal para-proteinaemia of 7.83g/l and elevated levels of serum TSH and prolactin. In this case the Castleman's disease is localised and the lymphoma preceded the Castleman's disease.  

Key words: POEMS syndrome, Castleman’s disease, non-Hodgkin’s lymphoma, plasmacytoma

doi: 10.4038/cmj.v54i2.872

Ceylon Medical Journal Vol. 54, No. 2, June 2009 pp68-69

DOI: https://doi.org/10.4038/cmj.v54i2.872
How to Cite: Parakramawansha, K.P.R.C., Wijeweera, I., Ratnatunga, N. and Sumanasekara, W.G.V., 2009. A case of POEMS syndrome with mixed hyaline vascular and plasma. Ceylon Medical Journal, 54(2), pp.68–69. DOI: http://doi.org/10.4038/cmj.v54i2.872
Published on 24 Jul 2009.

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