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Hepatitis B vaccine immunogenicity among nurses of a hospital

Authors:

V Piratheepkumar ,

Department of Pathology, Faculty of Medicine, University of Jaffna, LK
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S Kulendran,

Department of Pathology, Faculty of Medicine, University of Jaffna, LK
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S Nadarajah,

Department of Community and Family Medicine, Faculty of Medicine, University of Jaffna, LK
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K Murugananthan

Department of Pathology, Faculty of Medicine, University of Jaffna, LK
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Abstract

The aim of this study was to determine the factors affecting hepatitis B vaccine immunogenicity among nursing staff of Teaching Hospital, Jaffna. 152 nursing staffs were recruited from April to July 2013. Those who received three doses had 7.7% failure rate in developing protective immune response. Failure rates were 20% in those who received one dose and 10.6% in two doses. Following vaccination, participants who had chickenpox had a failure rate of 75% (n=13; p=0.02). Pregnancy significantly impaired protective immunity among those who received two doses (p=0.03). Three doses of hepatitis B vaccine may not be sufficient to protect the vaccinees. Therefore assessment of HBsAb titres is warranted after vaccination.

DOI: http://dx.doi.org/10.4038/cmj.v59i2.7065

Ceylon Medical Journal 2014; 59: 59-60

DOI: https://doi.org/10.4038/cmj.v59i2.7065
How to Cite: Piratheepkumar, V., Kulendran, S., Nadarajah, S. and Murugananthan, K., 2014. Hepatitis B vaccine immunogenicity among nurses of a hospital. Ceylon Medical Journal, 59(2), pp.59–60. DOI: http://doi.org/10.4038/cmj.v59i2.7065
Published on 26 Jun 2014.
Peer Reviewed

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