Start Submission Become a Reviewer

Reading: Identification of aero-allergen sensitization in children seeking treatment for bronchial as...

Download

A- A+
Alt. Display

Papers

Identification of aero-allergen sensitization in children seeking treatment for bronchial asthma at a tertiary care hospital for children in Sri Lanka

Authors:

MP Senanayake,

Department of Paediatrics, Faculty of Medicine, University of Colombo, LK
X close

R de Silva,

Medical Research Institute, Colombo 8, LK
X close

MDCJP Jayamanna,

Department of Paediatrics, Faculty of Medicine, University of Colombo, LK
X close

JASSK Jayasinghe,

Department of Paediatrics, Faculty of Medicine, University of Colombo, LK
X close

D Ratnayake,

Medical Research Institute, Colombo 8, LK
X close

V Jayasuriya,

Department of Community Medicine, Faculty of Medical Sciences, University of Sri Jayawardanapura, LK
X close

GN Malavige

Department of Microbiology, Faculty of Medical Sciences, University of Sri Jayawardanapura,, LK
X close

Abstract

Objectives Despite a significant rise in asthma globally as well as in Sri Lanka, data regarding allergen sensitization patterns and other risk factors for asthma are not available. Therefore, we set out to determine the allergen sensitization patterns in children with asthma in Sri Lanka.

Methods Skin prick testing for common indoor aeroallergens (cockroach, cat, dog, house dust mite, moulds) were carried out in 156 children with bronchial asthma at Lady Ridgeway Hospital for Children.

Results 49.1% of the patients were sensitized to at least one allergen and 6.4% were sensitized to three or more allergens. Of the children 37.8% tested positive to house dust mite, 23.7% to cockroach, 5.8% to indoor moulds, 12.2% to cats and 8.9% to dogs. Allergen sensitization was significantly less in children aged four years or younger than in older children (p<0.0001). A family history of asthma or allergic rhinitis (AR) was a significant risk factor (p<0.0001) for allergen sensitization (OR 10.9, 95% CI 3.9 to 30.1). Frequency of symptoms was significantly higher in those who used firewood alone compared to those who used other fuels (OR 2.5, 95% CI 1.1 to 5.8).

Conclusions Sensitization to aero-allergens was seen in a majority of children with asthma. Sensitization was significantly more in children above 4 years of age. Patients with more frequent symptoms and with AR were more likely to be sensitized to allergens.

DOI: http://dx.doi.org/10.4038/cmj.v59i3.7469

Ceylon Medical Journal 2014; 59: 89-93

DOI: https://doi.org/10.4038/cmj.v59i3.7469
How to Cite: Senanayake, M., de Silva, R., Jayamanna, M., Jayasinghe, J., Ratnayake, D., Jayasuriya, V. and Malavige, G., 2014. Identification of aero-allergen sensitization in children seeking treatment for bronchial asthma at a tertiary care hospital for children in Sri Lanka. Ceylon Medical Journal, 59(3), pp.89–93. DOI: http://doi.org/10.4038/cmj.v59i3.7469
Published on 29 Sep 2014.
Peer Reviewed

Downloads

  • PDF (EN)

    comments powered by Disqus