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Original article

Construct validity and reliability of EQ-5D-3L for stroke survivors in a lower middle income setting

Authors:

P. K. B. Mahesh ,

University of Melbourne, AU
About P. K. B.
Melbourne School of Population and Global Health
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M. W. Gunathunga,

University of Colombo, LK
About M. W.
Faculty of Medicine
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S. Jayasinghe,

University of Colombo, LK
About S.
Faculty of Medicine
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S. M. Arnold,

Office of Regional Director of Health Services, Colombo,, LK
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S. Senanayake,

Queensland University of Technology, AU
About S.
Austalian Centre for Healh Services Innovation
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C. Senanayake,

Queensland University of Technology, AU
About C.
Austalian Centre for Healh Services Innovation
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L. S. D. De Silva,

Queensland University of Technology, AU
About L. S. D.
Austalian Centre for Healh Services Innovation
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S. Kularatna

Queensland University of Technology, AU
About S.
Austalian Centre for Healh Services Innovation
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Abstract

Introduction

Stroke is a leading disease accounting for burden of chronic NCDs especially in lower and lower-middle income (LMI) settings. Quality of Life (QOL) is considered as an important facet of determination of success of patient management. EQ-5D-3L is a generic QOL tool. It provides an index score amalgamating responses for five descriptive questions and a visual analogue scale (VAS) value.

Objectives

To assess the validity and reliability of EQ-5D-3L for stroke patients in Sri Lanka, which is a LMI setting.

Methods

A descriptive cross sectional study was done among 100 stroke survivors among whom 50 each were managed at an ambulatory setting and an in-ward setting. A second wave of data collection was done for reliability analysis among one half of participants. The validity of EQ-5D-3L was assesses with five a-priori hypotheses. Reliability was assessed with test-retest method and with internal consistency. Non parametric Mann Whitney U test and Spearman correlation coefficients were used in the analysis.

Results

The EQ-5D index scores had significant positive correlation with SF-36 domain scores (p<0.001). The EQ-5D VAS scores had significant positive correlation with SF-36 domain scores (p<0.01). Index and VAS values of the EQ-5D were proved to be valid in known-group comparison (p<0.001). Participants reporting some kind of impairment for EQ-5D-3L dimensions had lower SF-36 domain scores. All the kappa values in the analysis of test-retest method were significant (p<0.001). For the VAS score, the Spearman correlation coefficient in test-reter analysis was 0.993 (p<0.001). Cronbach’s alpha value was 0.928.

Conclusions

and Recommendations EQ-5D-3L questionnaire demonstrates construct validity and a is a reliable toolin measuring QOL among stoke survivors in Sri Lanka.

 

DOI: https://doi.org/10.4038/cmj.v64i2.8891
How to Cite: Mahesh, P.K.B., Gunathunga, M.W., Jayasinghe, S., Arnold, S.M., Senanayake, S., Senanayake, C., De Silva, L.S.D. and Kularatna, S., 2019. Construct validity and reliability of EQ-5D-3L for stroke survivors in a lower middle income setting. Ceylon Medical Journal, 64(2), pp.52–58. DOI: http://doi.org/10.4038/cmj.v64i2.8891
Published on 26 Jul 2019.
Peer Reviewed

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