Start Submission Become a Reviewer

Reading: Clinicopathological characteristics and oncological outcomes of patients with renal cell car...

Download

A- A+
Alt. Display

Original articles

Clinicopathological characteristics and oncological outcomes of patients with renal cell carcinoma

Authors:

Madura Ambegoda ,

Colombo South Teaching Hospital, Dehiwala, LK
About Madura
Department of Urology
X close

Rakitha Paranamanna,

Colombo South Teaching Hospital, Dehiwala, LK
About Rakitha
Department of Urology
X close

Sagara Kumara,

Colombo South Teaching Hospital, Dehiwala, LK
About Sagara
Department of Urology
X close

Balasingam Balagobi,

Colombo South Teaching Hospital, Dehiwala, LK
About Balasingam
Department of Urology
X close

Cherine Sosai,

Colombo South Teaching Hospital, Dehiwala, LK
About Cherine
Department of Pathology
X close

Arunasalam Pathmeswaran,

University of Kelaniya, Ragama, LK
About Arunasalam
Department of Public Health, Faculty of Medicine
X close

Anuruddha Abeygunasekera

Colombo South Teaching Hospital, Dehiwala,, LK
About Anuruddha
Department of Urology
X close

Abstract

Although certain characteristics of renal cell carcinoma (RCC) seen in Sri lanka are different to the developed world and incidence is rising, no data on oncological outcome and patient survival are avaialble. A hospitalbased cohort study was done in a tertiary referral centre over a period of eight years (2012-2019). A total of 285 newly diagnosed RCC had a mean follow-up period of 28.3 months. Radical nephrectomy was performed in 189 patients while 91 patients had partial nephrectomy. Clear cell RCC which was seen in 231 (81.1%) patients while papillary RCC was seen in 43 (15.1%). There were 54 deaths during the follow-up. The 30-day postoperative mortality was 2.1%. Thirty (10.5%) patients developed metastases while three patients developed local recurrences. The overall five-year survival rate was 72.8%(95% CI=65.9-80.5). Five-year survival of papillary RCC (60.5%) was lower than clear cell RCC (74.1%). Tumour stage, presence of metastases and histological grade of the tumour influenced the survival. Gender (p=0.3), histological type (p=0.5) or type of surgery (p=0.2) had no statistically significant effect on survival.

DOI: https://doi.org/10.4038/cmj.v65i3.9187
How to Cite: Ambegoda, M., Paranamanna, R., Kumara, S., Balagobi, B., Sosai, C., Pathmeswaran, A. and Abeygunasekera, A., 2020. Clinicopathological characteristics and oncological outcomes of patients with renal cell carcinoma. Ceylon Medical Journal, 65(3), pp.62–66. DOI: http://doi.org/10.4038/cmj.v65i3.9187
Published on 10 Nov 2020.
Peer Reviewed

Downloads

  • PDF (EN)

    comments powered by Disqus