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Comparison of glycaemic control and anthropometric parameters before and after Ramadan fasting in a selected cohort of patients with type 2 diabetes mellitus in Sri Lanka

Authors:

Mohamed Shafras ,

University of Peradeniya, LK
About Mohamed
Postgraduate Institute of Science
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Lakshika Monaragala,

National Hospital, LK
About Lakshika
Department of Diabetes and Endocrinology
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Isha Samarakkody,

National Hospital, LK
About Isha
Department of Diabetes and Endocrinology
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Rafeek Rukshan Ahamed,

National Hospital, LK
About Rafeek Rukshan
Department of Diabetes and Endocrinology
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Lakshika Nawarathna,

University of Peradeniya, LK
About Lakshika
Department of Statistics and Computer Science
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Mohamed Sanas,

National Hospital, LK
About Mohamed
Department of Diabetes and Endocrinology
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Charles Antonypillai

National Hospital, LK
About Charles
Department of Diabetes and Endocrinology
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Abstract

Introduction: The majority of Sri Lankan Moors fast during Ramadan. This may have an effect on their glycaemic control and anthropometric parameters. However, limited information exists about the impact of Ramadan fasting on diabetes in Sri Lanka.


Objectives: The main objective of this study was to investigate the effect of Ramadan fasting on glycaemic control and anthropometric parameters in patients with type 2 diabetes mellitus (T2DM). Patients were also observed for symptoms of hypoglycaemia, timing and association with different antidiabetic agents.


Methods: One hundred and twenty Sri Lankan Moors with T2DM were recruited for this study. Biochemical investigations and anthropometric parameters were done before and after Ramadan fasting. The statistical analysis was done with paired t test to compare glycaemic control and anthropometric parameters before and after Ramadan.


Results: There was a significant decrease in body weight (mean body weight 66.17 to 65.52 kg; p= < 0.001) and waist circumference (93.84 to 92.16cm; p= < 0.001). However, the glycaemic control worsened in all patients during Ramadan with rise in mean fructosamine value of 354.1 to 996.9µmol/L. Out of 104 participants 43 participants experienced symptoms of hypoglycaemia.  


Conclusions: The current study showed an improvement in the body weight and waist circumference during Ramadan fasting, however the glycaemic control has been worsened. More follow-up studies are warranted in order to draw a conclusion on the effect of Ramadan fasting in glycaemic control and anthropometric parameters in diabetes patients.

DOI: https://doi.org/10.4038/cmj.v65i4.9276
How to Cite: Shafras, M., Monaragala, L., Samarakkody, I., Ahamed, R.R., Nawarathna, L., Sanas, M. and Antonypillai, C., 2020. Comparison of glycaemic control and anthropometric parameters before and after Ramadan fasting in a selected cohort of patients with type 2 diabetes mellitus in Sri Lanka. Ceylon Medical Journal, 65(4), pp.79–85. DOI: http://doi.org/10.4038/cmj.v65i4.9276
Published on 31 Dec 2020.
Peer Reviewed

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