Original articles
Diagnostic yield and outcome of transrectal ultrasound-guided prostate biopsy in Sri Lanka
Authors:
Umesh Jayarajah ,
Colombo South Teaching Hospital, Dehiwala, LK
About Umesh
Department of Urology
Sanjeewa Vidanapathirana,
Colombo South Teaching Hospital, Dehiwala, LK
About Sanjeewa
Department of Urology
Shinthujaa Mahadewa,
Colombo South Teaching Hospital, Dehiwala, LK
About Shinthujaa
Department of Urology
Saranga Wijayagunawardena,
Colombo South Teaching Hospital, Dehiwala, LK
About Saranga
Department of Urology
Velayuthan Senthan,
Colombo South Teaching Hospital, Dehiwala, LK
About Velayuthan
Department of Urology
Kapila Edirisinghe,
Colombo South Teaching Hospital, Dehiwala, LK
About Kapila
Department of Urology
Madura Ambegoda,
Colombo South Teaching Hospital, Dehiwala, LK
About Madura
Department of Urology
Anuruddha Mahasen Abeygunasekera
Colombo South Teaching Hospital, Dehiwala
About Anuruddha
Department of Urology
Abstract
Introduction: The study was aimed to determine the diagnostic yield and outcome of transrectal ultrasoundguided prostate biopsy (TRUSPB) in a cohort of Sri Lankan men.
Methods: A prospective study was conducted among 333 (median age: 70 years, range: 48-88) men from a single urology unit. All patients underwent TRUSPB for persistently elevated serum prostate specific antigen (PSA) ≥4.00 ng/mL or suspicious rectal examination.
Results: The prostate cancer (PCa) detection rate was 57.7%. The PCa detection rate for PSA levels of 4.00 to <10, 10.00 to <20, 20.00 to <40, 40.00 to <100 and ≥100.00 ng/mL were 15/43 (34.9%), 23/88 (26.1%), 41/72 (56.9%), 51/63 (81.0%) and 60/62 (96.8%) respectively. Ten patients required further biopsies for rising PSA despite a first benign biopsy and three had PCa. Mild complications were identified in 6.9% (n=23).
Conclusions: The high PCa detection rate probably reflects the difference in our policy to perform biopsies only when serum PSA level is persistently elevated. TRUSPB appears to have a satisfactory yield with acceptable level of complications in the Sri Lankan resource limited setting.
How to Cite:
Jayarajah, U., Vidanapathirana, S., Mahadewa, S., Wijayagunawardena, S., Senthan, V., Edirisinghe, K., Ambegoda, M. and Abeygunasekera, A.M., 2021. Diagnostic yield and outcome of transrectal ultrasound-guided prostate biopsy in Sri Lanka. Ceylon Medical Journal, 66(4), pp.162–167. DOI: http://doi.org/10.4038/cmj.v66i4.9506
Published on
31 Dec 2021.
Peer Reviewed
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