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Diagnostic yield and outcome of transrectal ultrasound-guided prostate biopsy in Sri Lanka

Authors:

Umesh Jayarajah ,

Colombo South Teaching Hospital, Dehiwala, LK
About Umesh
Department of Urology
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Sanjeewa Vidanapathirana,

Colombo South Teaching Hospital, Dehiwala, LK
About Sanjeewa
Department of Urology
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Shinthujaa Mahadewa,

Colombo South Teaching Hospital, Dehiwala, LK
About Shinthujaa
Department of Urology
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Saranga Wijayagunawardena,

Colombo South Teaching Hospital, Dehiwala, LK
About Saranga
Department of Urology
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Velayuthan Senthan,

Colombo South Teaching Hospital, Dehiwala, LK
About Velayuthan
Department of Urology
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Kapila Edirisinghe,

Colombo South Teaching Hospital, Dehiwala, LK
About Kapila
Department of Urology
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Madura Ambegoda,

Colombo South Teaching Hospital, Dehiwala, LK
About Madura
Department of Urology
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Anuruddha Mahasen Abeygunasekera

Colombo South Teaching Hospital, Dehiwala
About Anuruddha
Department of Urology
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Abstract

Introduction: The study was aimed to determine the diagnostic yield and outcome of transrectal ultrasoundguided prostate biopsy (TRUSPB) in a cohort of Sri Lankan men.

 

Methods: A prospective study was conducted among 333 (median age: 70 years, range: 48-88) men from a single urology unit. All patients underwent TRUSPB for persistently elevated serum prostate specific antigen (PSA) ≥4.00 ng/mL or suspicious rectal examination.

 

Results: The prostate cancer (PCa) detection rate was 57.7%. The PCa detection rate for PSA levels of 4.00 to <10, 10.00 to <20, 20.00 to <40, 40.00 to <100 and ≥100.00 ng/mL were 15/43 (34.9%), 23/88 (26.1%), 41/72 (56.9%), 51/63 (81.0%) and 60/62 (96.8%) respectively. Ten patients required further biopsies for rising PSA despite a first benign biopsy and three had PCa. Mild complications were identified in 6.9% (n=23).

 

Conclusions: The high PCa detection rate probably reflects the difference in our policy to perform biopsies only when serum PSA level is persistently elevated. TRUSPB appears to have a satisfactory yield with acceptable level of complications in the Sri Lankan resource limited setting.
DOI: https://doi.org/10.4038/cmj.v66i4.9506
How to Cite: Jayarajah, U., Vidanapathirana, S., Mahadewa, S., Wijayagunawardena, S., Senthan, V., Edirisinghe, K., Ambegoda, M. and Abeygunasekera, A.M., 2021. Diagnostic yield and outcome of transrectal ultrasound-guided prostate biopsy in Sri Lanka. Ceylon Medical Journal, 66(4), pp.162–167. DOI: http://doi.org/10.4038/cmj.v66i4.9506
Published on 31 Dec 2021.
Peer Reviewed

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